Alzheimer’s Disease: A Challenge In The Face Of Modern Era
DOI:
https://doi.org/10.12723/mjs.45.3Keywords:
Alzheimer, β-amyloid, β-secretase, BACE1, Blood-brain barrier (BBB)Abstract
Alzheimer’s disease (AD) is a devastating disease which affects the mental capacity and hence the standard of life of patients suffering from this disease. The accumulation of β-amyloid plaques and tau tangles has been found to be central to the disease. Over the years, research on β-secretase has become known as a hopeful target for the exploration of AD. A number of drugs have been approved by the US-FDA which meliorates only some of the symptoms of AD, but do not help in modifing the principal disease mechanisms.
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Copyright (c) 2018 Anil K Agarwal, Roshni Varghese, Gowri Soman, K Krishna Kumar, Joyal Joshy
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