Synthesis and Characterization of Benzoxazinone Derivatives

Authors

  • Nefisath P Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.
  • Vishwanatha P Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.
  • Sudhakar Y N Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

DOI:

https://doi.org/10.12723/mjs.45.4

Keywords:

Benzoxazinone, Quinazolinone

Abstract

The present work reports synthesis and characterization of different benzoxazinone derivatives. 2-methyl-7-nitro-4H-3,1-benzoxazin-4-one was prepared by refluxing 4- nitroanthranilic acid with acid anhydride. Derivatives of 2-methyl-7-nitro-4H-3,1-benzoxazin-4-one were synthesized by condensation of it with different anilines. Elemental analysis and NMR spectral studies were used to confirm the formation of compounds.

Author Biographies

Nefisath P, Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

Vishwanatha P, Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

Sudhakar Y N, Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire – 574240.

References

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D. A. Patil et. al., “Synthesis of 2, 3-Disubstituted-Quinazolin-4-(3H)-ones” Mini – Reviews in Medicinal Chemistry, vol.11, 633-641, 2011.

Chatrsal Singh Rajput and Pushkar Singh Bora, A review: quinazolin-4-ones as antifungal agents, International journal of Pharma and Bio-Scinces, vol.3(4):P, 119-132, 2012.

Gollapalli Naga Raju et. al., “Potential antimicrobial activities of quinazolinone derivatives”, Journal of Chemical and Pharmaceutical Research, vol. 7(5), 1279-1287, 2015.

M. K. Shivananda and B. Shivarama Holla, “Antifungal activity studies of some quinazolinone derivatives”, Journal of Chemical and Pharmaceutical Research, vol. 3(3), 2011, 83-86.

Additional Files

Published

2021-08-16

Issue

Vol. 17 No. 2 (2018): Mapana Journal of Sciences

Section

Research Articles

License

Copyright (c) 2018 Nefisath P, Vishwanatha P, Sudhakar Y N

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.