Design an Efficient Method for the Synthesis of 2-(1,3-Diphenyl-1H-Pyrazol-4-yl)-1H-Benzo[d]imidazole
DOI:
https://doi.org/10.12723/mjs.53.3Keywords:
Benzoimidazoles, pyrazoles, imidazolesAbstract
A simple, highly efficient and environmentally friendly method has been developed for the synthesis of 2-(1,3-diphenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazole by using Gadolinium(III) trifluoromethanesulfonate catalyst and ethanol reflux reaction conditions By using this method. 12 new 2-(1,3-diphenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazole derivatives were synthesized under optimized reactions conditions. All these new products structures are confirmed by spectral analysis. By this method, we achieved imidazole derivatives with more operational simplicity, short reaction time and good yields (up to 85%).
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