Vol. 19 No. 2 (2020): Mapana Journal of Sciences
Perspective

Application of FBRM Technology in the crystallization process (A perspective)

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  • Vandana R,
  • Pragya Anand
Vandana R
Department of Chemistry, CHRIST (Deemed to be University)
Bio
Pragya Anand
Department of Chemistry, CHRIST (Deemed to be University)
Bio

Published 2021-08-28

Keywords

  • Solvent selection,
  • Solubility,
  • Seeding,
  • PAT techniques

Copyright (c) 2020

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Abstract

Crystallisation is a two-step process, Step 1 being Nucleation (commencement of the new phase) & Step 2 being subsequent growth of nuclei to crystals. The pre-requisite for crystallisation to occur is the formation of a super-saturated solution, which is in a non-equilibrium state. From this point forward, the process is all about moving toward an equilibrium point, to achieve crystal formation.

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