The Menispermaceae family of plants and its action against infectious diseases: A review
DOI:
https://doi.org/10.12723/mjs.53.4Keywords:
Menispermaceae family, alkaloids, benzylisoquinoline alkaloids, protoberberine alkaloidsAbstract
India is a country where traditional medicines play a huge role in primary health care. Ayurveda, Siddha, Unani are some of the well-known traditional practices used for centuries and these traditional systems are highly dependent on medicinal plants. India is a rich source of these medicinal plants. The Western Ghats is known for its rich diversity, richness, and presence of endemic species. Menispermaceae family consists of more than 400 species; all are reported to have high medicinal values. Different classes of alkaloids present may be the major reason for these biological potentials, which are of great interest for various research groups. Benzylisoquinoline alkaloids, protoberberine alkaloids, aporphine alkaloids, etc are some examples for the alkaloids present in the Menispermaceae family. This review deals with the phytochemistry and pharmacological study of the Menispermaceae family and the action of these plants against various infectious diseases, described in Ayurveda.
References
(1) McMurry, J. E., Secondary Metabolites:An Introduction To Natural Product Chemistry, Org. Chem. With Biol. Appl. 2009, 1016–1046.
(2) Müller, H.; Brackhagen, O.; Brunne, R.; Henkel, T.; Reichel, F. Natural Products in Drug Discovery, Ernst Schering Res. Found. Workshop, 2000, No. 32, 205–216.
(3) Maria, J.; Filho, B., Alkaloids of the Menispermaceae, 2015.
(4) Gilbert, M. G.,Menispermaceae, 1–31.
(5) Shine, V. J.; Anuja, G. I.; Suja, S. R.; Raj, G.; Latha, P. G., J. Bioassay Guided Fractionation of Cyclea Peltata Using in Vitro RAW 264.7 Cell Culture, Antioxidant Assays and Isolation of Bioactive Compound Tetrandrine, J. Ayurveda Integr. Med. 2018, 5–10.
(6) Anubrata Paul, A. V. A. S. R.; SRM. Int. J. of Pharma and Bio Sciences, Preliminary phytochemical screening of six medicinal 2016, 7 (1), 77–81.
(7) Semwal, D. K.; Semwal, R. B. Efficacy and Safety of Stephania Glabra: An Alkaloid-Rich Traditional Medicinal Plant. Nat. Prod. Res. 2015, 29 (5), 396–410.
(8) Jahan, R.; Khatun, M. A.; Nahar, N.; Jahan, F. I.; Chowdhury, A. R.; Nahar, A.; Seraj, S.; Mahal, M. J.; Khatun, Z.; Rahmatullah, M. Use of Menispermaceae Family Plants in Folk Medicine of Bangladesh., Adv. Nat. Appl. Sci. 2010, 4 (1), 1–9.
(9) Kumar, D.; Badoni, R.; Semwal, R.; Kumar, S.; Jas, G.; Singh, P.; Rawat, U. The Genus Stephania ( Menispermaceae ): Chemical and Pharmacological Perspectives. J. Ethnopharmacol., J. Ethnopharmacol. 2010, 132 (2), 369–383.
(10) Md. Moniruzzaman, Sarwar, Hossain.; Partha, Sharoti, Bhattacharjee. Author ’ s Accepted Manuscript of Stephania Japonica.; J. of Ethnopharmacology, 2016,
(11) Das, A. K.; Molla, S.; Sykat, M. R.; Ali, A.; Haque, T.; Rahman, L.; Babu, I. M.; Islam, H.; Islam, M. T., Phytochemical and Pharmacological Review on Stephania Japonica. 2019, 14(1), 10433-10436
(12) Semwal, D. K., Natural Product Research : Formerly Natural Product Letters Efficacy and Safety of Stephania Glabra : An Alkaloid-Rich Traditional Medicinal Plant, 2014, 37–41.
(13) Jangir, S.; Wing, P., A Review on Cocculus Pendulus (j. r. Forst. & g. Forst.) Diels: Traditional Uses, Phytochemistry and Pharmacological Properties, Indian Journal of Drugs, 2016, 4 (2), 57–62
(14) Rakkimuthu, R.; Kavithakrishnan, R.; Suganyadevi, P.; Aravinthan, K. O f Phytom Quantita Ative Phyt Tochemic Cal Analys Sis and Th Eir Antiox Xidant Act Tivity of Cocculus Hirsutu Us ( l .) Die Els Fruit. M.; Int. J. of Phytomedicine, 2012, 4 (4) 447-455
(15) Rishikesh, Meena.; Mukesh, Kumar, Meena.; Herbal & Alternative Medicine. 2017, 1 (2).
(16) Sharanabasappa, A, Patil.; Sujaya, M.; Saraswati, B, Patil.; A Phrodisiac and Phytochemical Studies of Cocculus Hirsutus Extracts in a Lbino Rats., Asian Pacific Journal of Reproduction, 2014, 3 (1), 23–29.
(17) Satya, V.; Paridhavi, M.; Isolation and Characterization of Compounds from Fruits of Anamirta Cocculus ( Linn .), Int. J. of Pharmacognosy and Phytochemical Research, 2016, 8 (4), 619–622.
(18) Kshetrimayum, B. Medicinal Plants and Its Therapeutic Uses. Omics ebooks group, 2017.
(19) Manu, A.; Tanvi, S.; Anu, D.; Neeraj, B.; Ahmad, S. A A., An inside review of cissampelos pareira linn: a potential medicinal plant of india, Int. Research Journal of Pharmacy 2012, 3 (12), 38–41.
(20) De Wet, H.; Van Heerden, F. R.; Van Wyk, B. E., Alkaloidal Variation in Cissampelos Capensis (Menispermaceae), Molecules 2011, 16 (4), 3001–3009.
(21) Kundu, S.; Ahmed, K. M. M. M.; Mahavidyalaya, R. A., A Traditional Indian Herbs And Its Medicinal Importance-An Ayurvedic Approach with Contemporary View, Int. J. of Ayurvedic and Herbal Medicine, 2016, 4, 2260–2267.
(22) Singh, G.; Saxena, K.; research article phytochemical analysis of tinospora cordifolia by using different solvent extract, Int. J. of Current Research, 2017, 9(11), 61213-61215,
(23) Sharma, R.; Amin, H.; Galib; Prajapati, P. K. Antidiabetic Claims of Tinospora Cordifolia (Willd.) Miers: Critical Appraisal and Role in Therapy, Asian Pac. J. Trop. Biomed. 2015, 5 (1), 68–78.
(24) Polu, P. R.; Nayanabhirama, U.; Khan, Di Preliminary Evaluation of In Vitro Anti-Proliferative Activity of Tinospora Cordifolia (Willd) Miers and Estimation of Berberine Content by HPLC, Der Pharmacia Lettre, 2017, 9 (6), 82-95
(25) Sengupta, S.; Mukherjee, A.; Goswami, R.; Basu, S., S. Hypoglycemic Activity of the Antioxidant Saponarin, Characterized as α-Glucosidase Inhibitor Present in Tinospora Cordifolia. J. Enzyme Inhib. Med. Chem. 2009, 24 (3), 684–690.
(26) Patel, M. B.; Mishra, S. Phyther. S. Isoquinoline Alkaloids from Tinospora Cordifolia Inhibit Rat Lens Aldose Reductase. Phyther. Res. 2012, 26 (9), 1342–1347.
(27) Bala, M.; Pratap, K.; Verma, P. K.; Singh, B.; Padwad, Y., J. of Ethnopharmacology, 2015, S0378-8741.
(28) Pan, L.; Terrazas, C.; Lezama-davila, C. M.; Rege, N.; Gallucci, J. C.; Satoskar, A. R.; Kinghorn, A. D., a Sulfur-Containing Clerodane Diterpene Glycoside from Tinospora Cordifolia. Org. letters, 2012, 14(8), 749–750.
(29) Dweck, A. C.; Cavin J. P., Andawali (Tinospora crispa) - a review, Pers. Care Mag. 2006, 33–39.
(30) Praman, S.; Mulvany, M. J.; Williams, D. E.; Andersen, R. J.; Jansakul, C., J. Crude Extract and Purified Components Isolated from the Stems of Tinospora Crispa Exhibit Positive Inotropic Effects on the Isolated Left Atrium of Rats. J.Ethnopharmacol, 2013, 149 (1), 123–132.
(31) Parveen, A.; Huang, Y.; Fantoukh, O.; Alhusban, M.; Raman, V.; Wang, Y. H.; Wang, W.; Ali, Z.; Khan, I. A. Rearranged Clerodane Diterpenoid from Tinospora Crispa. Nat. Prod. Res. 2019, 0 (0), 1–8.
(32) Amom, Z.; Azman, K. F.; Ismail, N. A.; Shah, Z. M.; Arshad, M. S. M., An aqueous extract of tinospora crispa possesses antioxidative properties and reduces atherosclerosis in hypercholesterolemic-induced rabbits J. Food Biochem. 2011, 35 (4), 1083–1098.
(33) Cachet, X.; Langrand, J.; Riffault-Valois, L.; Bouzidi, C.; Colas, C.; Dugay, A.; Michel, S.; Boucaud-Maitre, D., Clerodane Furanoditerpenoids as the Probable Cause of Toxic Hepatitis Induced by Tinospora Crispa, Sci. Rep. 2018, 8 (1), 1–11.
(34) Kongkathip, N.; Dhumma-upakorn, P.; Kongkathip, B.; Chawananoraset, K.; Sangchomkaeo, P.; Hatthakitpanichakul, S., S, Study on Cardiac Contractility of Cycloeucalenol and Cycloeucalenone Isolated from Tinospora Crispa, J. Ethnopharmacol. 2002, 83 (1–2), 95–99.
(35) Phienwej, H.; Swasdichira, I. si; Amnuoypol, S.; Pavasant, P.; Sumrejkanchanakij, P. P. Tinospora Crispa Extract Inhibits MMP-13 and Migration of Head and Neck Squamous Cell Carcinoma Cell Li, Asian Pac. J. Trop. Biomed. 2015, 5 (9), 738–743.
(36) Rollando, R., Combination of Hedyotis Corymbosa L. and Tinospora Crispa Ethanolic Extract Increase Cisplatin Cytotoxicity on T47D Breast Cancer Cells, Asian J. Pharm. Clin. Res. 2018, 11 (7), 171–177.
(37) Ibahim, M. J.; Wan-Nor, I. W. M. Z.; Narimah, A. H. H.; Nurul, A. Z.; Siti-Nur, S. S. A. R.; Froemming, G. A., Froemming, G. A, Anti-Proliperative and Antioxidant Effects of Tinospora Crispa (Batawali), Biomed. Res. 2011, 22 (1), 57–62.
(38) Xu, Y.; Niu, Y.; Gao, Y.; Wang, F.; Qin, W.; Lu, Y.; Hu, J.; Peng, L.; Liu, J.; Xiong, W., J Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora Crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice, Nat. Prod. 2017, 80 (8), 2319–2327.
(39) Lam, S. H.; Ruan, C. T.; Hsieh, P. H.; Su, M. J.; Lee, S, Hypoglycemic Diterpenoids from Tinospora Crispa, J. Nat. Prod. 2012, 75 (2), 153–159.
(40) Hamid, H. A.; Yusoff, M. M.; Liu, M.; Karim,M. R., α-Glucosidase and α-Amylase Inhibitory Constituents of Tinospora Crispa: Isolation and Chemical Profile Confirmation by Ultra-High Performance Liquid Chromatography-Quadrupole Time-of-Flight/Mass Spectrometry, J. Funct. Foods 2015, 16, 74–80.
(41) Gao, Y.; Niu, Y. F.; Wang, F.; Hai, P.; Wang, F.; Fang, Y. D.; Xiong, W. Y.; Liu, J. K. Clerodane Diterpenoids with Anti-Hyperglycemic Activity from Tinospora Crispa, Nat. Products Bioprospect. 2016, 6 (5), 247–255.
(42) Tushar, K. V.; Satheesh, George,; Remashree, A. Coscinium Fenstratum Review.Pdf. J. of Plant Sciences, 2008, 3(2), 133-145.
(43) B.K. Manjunatha, B. K. M.; Murthuza, S.; Sudharshan S.J, S. S.; Divakara R, D, R. Phytochemical Investigation and Hepatoprotective Activity of Coscinium Fenestratum Colebr., A Rare Endangered Spp., from Western Ghats of India Paripex - Indian J. Res. 2012, 2 (2), 14–16.
(44) Karthika, K.; Gargi, G.; Jamuna, S.; Paulsamy, S.; Ajmal Ali, M.; Al-Hemaid, F.; Soliman Elshikh, M.; Lee, The Potential of Antioxidant Activity of Methanolic Extract of Coscinium Fenestratum (Goetgh.) Colebr (Menispermaceae), J.; Saudi J. Biol. Sci. 2019, 26 (5), 1037–1042.
(45) Nair, G. M.; Narasimhan, S.; Shiburaj, S.; Abraham T,K Antibacterial Effects of Coscinium Fenestratum. Fitoterapia 2005, 76 (6), 585–587.
(46) Pinho, P. M. M.; Pinto, M. M. M.; Kijjoa, A.; Pharadai, K.; Díaz, J. G.; Herz, Protoberberine Alkaloids from Coscinium Fenestratum. W.; Phytochemistry 1992, 31 (4), 1403–1407.
(47) Keawpradub, N.; Dej-adisai, S. Songklanakarin J. S., Antioxidant and Cytotoxic Activities of Thai Medicinal Plants Named Khaminkhruea : Arcangelisia Flava, Coscinium Blumeanum and Fibraurea Tinctoria, Sci. Technol. 2005, 2 (27), 455–467.
(48) De Wet, H.; Struwig, M.; Van Wyk, B. E. Taxonomic Notes on the Genera Tiliacora and Tinospora (Menispermaceae) in Southern Africa, South African J. Bot. 2016, 103, 283–294.
(49) Vivek Kumar, T.; Vishalakshi, M.; Gangaraju, M.; Das, P.; Roy, P.; Banerjee, A.; Dutta Gupta,S., Evaluation of Antibacterial, Antioxidant and Nootropic Activities of Tiliacora Racemosa Colebr. Leaves: In Vitro and in Vivo Approach, Biomed. Pharmacother. 2017, 86, 662–668.
(50) Yogeshwari, C.; Kumudha, P., Phytochemical Evaluation of Tiliacora Racemosa Colebr. Using Gas Chromatography-Mass Spectrometry, Asian J. Pharm. Clin. Res. 2018, 11 (2), 350–353.
(51) Tripathi, Y. C.;Antifungal Activity of Alkaloids of Tiliacora Racemosa, National Academy Science Letters,1989, 12(3).
(52) Kamya, C. J.; Rau, A. R.; Subin, M. P., Phytochemical Analysis and Antibacterial Activity of Euphorbia Hirta Linn. and Tiliacora Acuminata Miers, Nat. Environ. Pollut. Technol. 2012, 11 (1), 95–98.
(53) Manda, R.; Seru, G.; Evaluation of Hypoglycaemic and Wound Healing Activities of Tiliacora Acuminata, J. of Chemical and Pharmaceutical Research, 2016, 8 (5), 494–497.
(54) Selvaraj, S. J.; Alphonse, I.; A New Lactone from Aerial Parts of Tiliacora Acuminata. Britto, S. J.; Indian J. Chem. - Sect. B Org. Med. Chem. 2008, 47 (6), 942–944.
(55) Hagel, J. M.; Facchini, P. J.; Benzylisoquinoline Alkaloid Metabolism: A Century of Discovery and a Brave New World, Plant Cell Physiol. 2013, 54 (5), 647–672.
(56) S., J. C.; S., M. M.; Ramesh, R. Evaluation of the Wound Healing Activity of Caesalpinia Bonducella and Cyclea Peltata Extracts in Experimentally Induced Diabetic Rats, Int. J. Pharm. Pharm. Sci. 2017, 9 (10), 211.
(57) Meena, J.; Santhy, K. S., Evaluation of the Antioxidant Potential of Methanol Extract of Cyclea Peltata in DAL Model, The Pharma Innovation Journal, 2015, 4 (1), 71–75.
(58) Sridhar, S. An in-vitro study on anti-inflammatory and anti- bacterial activities of ethyl acetate extract from the leaves of Cyclea peltata, Indo American J. of Pharmaceutical Sciences 2017, 4 (12), 4334–4342.
(59) Abraham, J.; Thomas, T. D., Antibacterial Activity of Medicinal Plant Cyclea Peltata (Lam) Hooks & Thoms., Asian Pacific J. Trop. Dis. 2012, 2, S280–S284.
(60) Shine, V. J.; Latha, P. G.; Shyamal, S.; Suja, S. R.; Anuja, G. I.; Sini, S.; Pradeep, S.; Rajasekharan, S., Gastric Antisecretory and Antiulcer Activities of Cyclea Peltata (Lam.) Hook. f. & Thoms. in Rats, J. Ethnopharmacol. 2009, 125 (2), 350–355.
(61) Sulaiman, C. T.; Balachandran, I., Chemical Profiling of an Indian Herbal Formula Using Liquid Chromatography Coupled with Electro Spray Ionization Mass Spectrometry, Spectrosc. Lett. 2014, 48 (3), 222–226.
(62) Dilip, C.; Saraswathi, R.; Krishnan, P. N.; Azeem, A. K.; Raseena; Azeez, A.; Ramya; jose, J., Comparitive Evaluation of Different Systems of Medicines and the Present Scenario of Chikungunya in Kerala.Asian Pac. J. Trop. Med. 2010, 3 (6), 443–447.
(63) Satyadev, K.; Jinesh, Kumar, Jain,; Swapnil, Singhai, role of bharangyadi kwath in the cases of visham jwara ( malaria), Int. J. of Development Research, 2017, 07, 13650–13654.
Additional Files
Published
Issue
Section
License
Copyright (c) 2020 Mapana Journal of Sciences
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
