Vol. 23 No. Special Issue 3 (2024): Mapana - Journal of Sciences
Research Articles

A Systematic Review and Meta-Analysis: Comparative Analysis of Psychotherapy and Pharmacotherapy for Treatment of Depression

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  • Diyasha Chakrabarti
Diyasha Chakrabarti
Christ (Deemed to be University)
DOI: https://doi.org/10.12723/mjs.sp3.9

Published 2024-11-06

Keywords

  • pharmacotherapy,
  • psychotherapy,
  • depression,
  • systematic review,
  • meta analysis,
  • HAMD
    • ...More
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Creative Commons License

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Abstract

Depression represents a significant health issue that can develop into a severe medical condition, especially when it recurs and manifests at moderate to severe levels of intensity. To identify the most effective treatment for depression, a rigorous study was conducted. The study used grid Hamilton Depression Rating Score (HAMD) scores to assess treatment efficacy and employed R software and MedCalc software to conduct a meta-analysis comparing the effectiveness of pharmacotherapy or psychotherapy or the combination of both. After eliminating duplicates, 280 papers were meticulously reviewed, and standardized mean differences and 95% confidence intervals were compared using a random effect model. The study found that combination therapy (combo-therapy) was more effective in reducing the HAMD than conventional monotherapy. These findings underscore the importance of identifying optimal treatment strategies for individuals suffering from depression.D

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