Published 2024-11-06
Keywords
- Machine Learning,
- Type2 Diabetes,
- Machine Learning Models,
- DNA Sequence,
- Model Construction
- BLAST, and AUGUSTUS. ...More
Copyright (c) 2024
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Abstract
This research paper addresses the challenge of objectively evaluating diverse biological characteristics through the classification of DNA sequences. Identifying DNA sequences in genomics research can aid in discovering novel protein activities, such as insulin, which regulates blood sugar levels in the human body. Diabetes, a prevalent chronic illness, is linked to changes in the insulin gene sequence. The study aims to develop a machine-learning model to categorize the insulin gene's DNA sequence and identify type 2 diabetes based on this transformation. The model's performance will be compared to existing machine-learning models. Additionally, the research seeks to identify unique gene variants of the insulin protein associated with diabetes prognosis and investigate the risk factors associated with these gene variants.
References
- Gulcin, İlhami. "Antioxidants and antioxidant methods: An updated overview." Archives of toxicology 94, no. 3 (2020): 651-715.
- Liu, Jun-Li, Irina Segovia, Xiao-Lin Yuan, and Zu-hua Gao. "Controversial roles of gut microbiota-derived short-chain fatty acids (SCFAs) on pancreatic β-cell growth and insulin secretion." International journal of molecular sciences 21, no. 3 (2020): 910.
- Neelakandan, S., J. Rene Beulah, L. Prathiba, G. L. N. Murthy, E. Fantin Irudaya Raj, and N. Arulkumar. "Blockchain with deep learning-enabled secure healthcare data transmission and diagnostic model." International Journal of Modeling, Simulation, and Scientific Computing 13, no. 04 (2022): 2241006.
- Jaishankar, B., Santosh Vishwakarma, Prakash Mohan, Aditya Kumar Singh Pundir, Ibrahim Patel, and N. Arulkumar. "Blockchain for Securing Healthcare Data Using Squirrel Search Optimization Algorithm." Intelligent Automation & Soft Computing 32, no. 3 (2022).
- Rathod, Sanjay. "Novel insights into the immunotherapy-based treatment strategy for autoimmune type 1 diabetes." Diabetology 3, no. 1 (2022): 79-96.
- Manimaran, Aridoss, Dhasarathan Chandramohan, S. G. Shrinivas, and N. Arulkumar. "A comprehensive novel model for network speech anomaly detection system using deep learning approach." International Journal of Speech Technology 23 (2020): 305-313.
- Artasensi, Angelica, Alessandro Pedretti, Giulio Vistoli, and Laura Fumagalli. "Type 2 diabetes mellitus: a review of multi-target drugs." Molecules 25, no. 8 (2020): 1987.
- Satish Kumar, T., S. Jothilakshmi, Batholomew C. James, M. Prakash, N. Arulkumar, and C. Rekha. "HHO-based vector quantization technique for biomedical image compression in cloud computing." International Journal of Image and Graphics (2021): 2240008.
- Awotunde, J. B., Ayo, F. E., Jimoh, R. G., Ogundokun, R. O., Matiluko, O. E., Oladipo, I. D., & Abdulraheem, M. (2021). Prediction and classification of diabetes mellitus using genomic data. In Intelligent IoT systems in personalized health care (pp. 235-292). Academic Press.
- Dias, Raquel, and Ali Torkamani. "Artificial intelligence in clinical and genomic diagnostics." Genome medicine 11.1 (2019): 1-12.
- Guo, Yang, Xuequn Shang, and Zhanhuai Li. "Identification of cancer subtypes by integrating multiple types of transcriptomics data with deep learning in breast cancer." Neurocomputing 324 (2019): 20-30.
- Lai, Hang, et al. "Predictive models for diabetes mellitus using machine learning techniques." BMC endocrine disorders 19.1 (2019): 1-9.
- Akbarzadeh, Mahdi, et al. "Evaluating machine learning-powered classification algorithms which utilize variants in the GCKR gene to predict metabolic syndrome: Tehran Cardio-metabolic Genetics Study." Journal of translational medicine 20.1 (2022): 1-12.
- Tigga, Neha Prerna, and Shruti Garg. "Prediction of type 2 diabetes using machine learning classification methods." Procedia Computer Science 167 (2020): 706-716.