Vol. 24 No. 1 (2025): Mapana Journal of Sciences
Review Articles

The Rise of Candida auris: A Review of a Globally Emerging Multidrug-Resistant Pathogen

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  • Vishal Bhoir,
  • Bela Nabar
Vishal Bhoir
Smt. CHM College, Ulhasnagar, Maharashtra, India
Bela Nabar
Microbiology Department, Smt. C.H.M. College, Ulhasnagar, Thane, Maharashtra, India
DOI: https://doi.org/10.12723/mjs.72.8

Published 2025-04-05

Keywords

  • Candida auris,
  • Multidrug resistance,
  • Antifungal resistance,
  • Fungal pathogenesis,
  • Global epidemiology,
  • Nasocomial outbreaks
    • ...More
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Abstract

The emerging multidrug-resistant fungal pathogen Candida auris poses a serious global public health threat. Since its identification in 2009, C. auris has rapidly spread worldwide and can cause difficult-to-treat nosocomial outbreaks and invasive infections with high mortality. C. auris exhibits frequent resistance to azoles, echinocandins, and polyenes, creating challenges for its clinical management. Its ability to persistently colonise patients and contaminate hospital environments also facilitates easy transmission. This review summarises current knowledge on C. Auris global epidemiology, mechanisms of antifungal resistance, limitations of current treatments, and emerging novel therapies under investigation. Ongoing research priorities include improving diagnostics, elucidating pathogenesis, developing new therapies, and optimising infection control. Mitigating the public health risks of this formidable fungal pathogen remains an urgent goal requiring focused efforts across multiple domains.

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