Research Articles
Published 2021-08-16
Keywords
- Dengue virus,
- 8-hydroxy quinoline,
- imidazole,
- 2-mercaptoimidazole
Copyright (c) 2018
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Abstract
8-Hydroxyqunoline derivatives were synthesised by treating 5-chloromethyl-8-hydroxy quinoline with imidazole and characterized using NMR and mass spectrometry. 2-mercaptoimidazole derivatives of 8-hydroxy quinoline were also synthesized and characterized. One of the compounds in this series has been tested for dengue activity along with other series of compounds, but did not show any activity against dengue virus.
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